Scientific and practical activity

The main areas of scientific and practical activitiy of Ukrainian anti-plague station are studying of problems of microbiology and epidemiology of a cholera, detection and analysis of circulation of causative agents of feral nidal infections, workings out and creation of information-analytical system of monitoring for infections which have the international significance and constitute a menace to mankind, problems of counteraction to biological terrorism, etc.

Among the main scientific and practical achievements there are:

• For the first time in Crimea existence of the natural focus of a tularemia on Kerch peninsula (1978) is detected and proved;
• Phages of cholera vibrios of О2, О22, О57 serogroups are received (1980);
• In rice-growing districts of Crimea the foci of a leptospirosis are detected (1980);
• For the first time in the world cholera vibrio of О57 serogroup is described (1981);
• The scheme of laboratory diagnostics of halophilic vibrios and system of tests for identification of pathogenic microorganisms are developed (1983);
• The causative agents of yersiniosis in the nature and among people in Crimea (1983) are detected;
• Circulation of a virus of a hemorrhagic fever with a renal syndrome in Crimea (1986) is established;
• 4 foci of a tick-borne encephalitis in Crimea are detected (1986);
• For the first time in the USSR some species of pathogenic vibrios - V. aesturianus, V. fluvialis, etc. are described (1986);
• The wide circulation of the causative agents of the Crimean-kongo hemorrhagic fever in Ukraine is detected (1987);
• One of the first in the USSR and Ukraine DNA-DNA probing is introduced (1989);
• Antibodies to the causative agents of a plague of black rats are detected on a transport-refrigerator ship «Yeysk bay» that there has arrived to sea port of Sevastopol for the first time in ports of the USSR and the CIS (1990);
• For the first time in Ukraine the system of the organisation of laboratory researches on a cholera is developed (1994) ;
• For the first time in Ukraine the polymerase chain reaction (PCR) for diagnosis of causative agents of dangerous infections (a cholera, a plague, an anthrax, a legionellosis, a leptospirosis, a tularemia, an yersiniosis, a borreliosis, an avian influenza, etc.) is introduced (1992-1995);
• Wide circulation of the causative agent of Lyme disease in Crimea is detected (1996);
• For the first time in the world diagnostic preparations for identification of halophilic vibrios are developed together with the Rostov research anti-plague institute, Russia (1996);
• For the first time in the world the kit of phages for a phage-typing of halophilic vibrios is developed together with the Rostov research anti-plague institute, Russia (1996);
• The concept of computer support of epidemiological surveillance for infectious diseases is developed (1996);
• The information-analytical system of monitoring of the biological characteristics of the causative agent is developed and introduced (1997);
• The complex scheme of researches of pathogenic vibrios is developed together with the Rostov research anti-plague institute, Russia (1998);
• For the first time the geographical information system is introduced into an epidemiology and medicine (1998);
• The copyright to scientific work „Monitoring system in epidemiology by the use of geographical information technology” is got (the certificate №11194, from 28.09.04) (2004);
• For the first time in Ukraine cholera vibrios О139 is secured from environment (2005);
• For the first time in Ukraine epizootologic and laboratory researches of wild migratory birds on avian influenza H5N1 in territory of Ukraine by method PCR in real time are lead (2005).